Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255587 | 0.93 | ALDH1A1 (0.48) | ALDH1A1TDP1TP53CYP3A4TSHR | |
| SCHEMBL9623125 | 0.83 | LMNA (0.46) | ALDH1A1TDP1LMNATP53CYP3A4 | |
| SCHEMBL8810590 | 0.81 | TP53 (0.48) | ALDH1A1TDP1LMNATP53CYP3A4 | |
| SCHEMBL8813253 | 0.81 | TP53 (0.44) | ALDH1A1TDP1LMNATP53CYP3A4 | |
| SCHEMBL11386370 | 0.81 | LMNA (0.45) | ALDH1A1TDP1LMNATP53CYP3A4 | |
| SCHEMBL3460439 | 0.79 | LMNA (0.48) | ALDH1A1TDP1LMNATP53CYP3A4 | |
| SCHEMBL8437242 | 0.79 | LMNA (0.48) | ALDH1A1TDP1LMNATP53CYP3A4 | |
| SCHEMBL11342785 | 0.79 | LMNA (0.48) | ALDH1A1TDP1LMNATP53CYP3A4 | |
| SCHEMBL3459612 | 0.79 | LMNA (0.48) | ALDH1A1TDP1LMNATP53CYP3A4 | |
| SCHEMBL11503745 | 0.79 | LMNA (0.48) | ALDH1A1TDP1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |