Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813031 | 0.98 | TP53 (0.33) | ACE2CA2TP53LMNA | |
| SCHEMBL8813650 | 0.91 | TP53 (0.30) | TP53 | |
| SCHEMBL8810597 | 0.83 | ACE2 (0.38) | ACE2CA2TP53FAAHLMNA | |
| SCHEMBL6729253 | 0.81 | — | — | |
| SCHEMBL8810688 | 0.81 | TP53 (0.39) | ACE2CA2TP53FAAHLMNA | |
| SCHEMBL8814285 | 0.79 | LMNA (0.42) | CA2TP53FAAHLMNA | |
| SCHEMBL8811142 | 0.79 | LMNA (0.42) | CA2TP53FAAHLMNA | |
| SCHEMBL8813035 | 0.78 | TP53 (0.41) | ACE2CA2TP53LMNA | |
| SCHEMBL13056220 | 0.78 | CA2 (0.38) | ACE2CA2TP53LMNA | |
| SCHEMBL4452016 | 0.78 | LMNA (0.47) | ACE2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |