Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | IL6ST | P40189 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | OGA | O60502 | 3/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810732 | 0.94 | EDNRA (0.34) | EDNRAIDH1IL6STALDH1A1LMNA | |
| SCHEMBL8811832 | 0.93 | IL6ST (0.35) | EDNRAIDH1IL6STALDH1A1LMNA | |
| SCHEMBL8810101 | 0.92 | IL6ST (0.36) | EDNRAIDH1IL6STALDH1A1LMNA | |
| SCHEMBL8809610 | 0.83 | EDNRA (0.44) | EDNRAALDH1A1LMNAMAPTOGA | |
| SCHEMBL7994175 | 0.79 | EDNRA (0.35) | EDNRAIDH1IL6STMAPTTRPV1 | |
| SCHEMBL13916990 | 0.79 | IL6ST (0.40) | EDNRAIDH1IL6STTRPV1STAT3 | |
| SCHEMBL13928771 | 0.79 | IL6ST (0.40) | EDNRAIDH1IL6STTRPV1STAT3 | |
| SCHEMBL8807087 | 0.77 | EDNRA (0.42) | EDNRAALDH1A1LMNAMAPTOGA | |
| SCHEMBL7986613 | 0.76 | EDNRA (0.34) | EDNRAIDH1IL6STLMNAMAPT | |
| SCHEMBL8807025 | 0.75 | EDNRA (0.41) | EDNRAALDH1A1LMNAMAPTOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792265-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-03 | — | — | EP | disclosed |