Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 3/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 2/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811832 | 0.98 | IL6ST (0.35) | IL6STSTAT3EDNRAIDH1OGA | |
| SCHEMBL8810732 | 0.95 | EDNRA (0.34) | IL6STSTAT3EDNRAIDH1OGA | |
| SCHEMBL8810786 | 0.92 | EDNRA (0.35) | IL6STSTAT3EDNRAIDH1OGA | |
| SCHEMBL8809676 | 0.84 | EDNRA (0.41) | EDNRAOGAEDNRBALDH1A1LMNA | |
| SCHEMBL8807025 | 0.82 | EDNRA (0.41) | EDNRAOGAEDNRBALDH1A1LMNA | |
| SCHEMBL7975894 | 0.80 | IL6ST (0.36) | IL6STSTAT3EDNRAIDH1EDNRB | |
| SCHEMBL8809082 | 0.79 | EDNRA (0.44) | EDNRAALDH1A1LMNAMAPTTGFBR1 | |
| SCHEMBL8807087 | 0.79 | EDNRA (0.42) | EDNRAOGAEDNRBALDH1A1LMNA | |
| SCHEMBL7986429 | 0.78 | IL6ST (0.35) | IL6STSTAT3EDNRAIDH1MAPT | |
| SCHEMBL8809339 | 0.77 | EDNRA (0.44) | EDNRAALDH1A1LMNAMAPTTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792265-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-03 | — | — | EP | disclosed |