Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 9/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807756 | 0.97 | ACACB (0.36) | LMNAPOLBALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8807979 | 0.86 | CTSK (0.43) | CAPN1 | |
| SCHEMBL8810844 | 0.84 | SMN1; SMN2 (0.39) | CAPN1 | |
| SCHEMBL8807293 | 0.83 | CAPN1 (0.42) | CAPN1 | |
| SCHEMBL8811205 | 0.82 | CAPN1 (0.52) | CAPN1CNR2 | |
| SCHEMBL8811215 | 0.82 | CAPN1 (0.52) | CAPN1CNR2 | |
| SCHEMBL8811225 | 0.82 | CAPN1 (0.52) | CAPN1CNR2 | |
| SCHEMBL8807772 | 0.79 | CAPN1 (0.51) | CAPN1 | |
| SCHEMBL8807749 | 0.79 | CAPN1 (0.51) | CAPN1 | |
| SCHEMBL8807765 | 0.79 | CAPN1 (0.51) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |