Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 15/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CAPNS1 | P04632 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSH | P09668 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807756 | 0.87 | ACACB (0.36) | CAPN1 | |
| SCHEMBL8811209 | 0.86 | LMNA (0.39) | CAPN1 | |
| SCHEMBL8810844 | 0.85 | SMN1; SMN2 (0.39) | CAPN1CAPNS1SMN1; SMN2 | |
| SCHEMBL8406532 | 0.84 | EPHX1 (0.38) | CAPN1CAPNS1 | |
| SCHEMBL8807293 | 0.84 | CAPN1 (0.42) | CAPN1CAPNS1 | |
| SCHEMBL8807983 | 0.82 | CTSK (0.56) | CTSKCAPN1CAPNS1 | |
| SCHEMBL8807975 | 0.82 | CTSK (0.56) | CTSKCAPN1CAPNS1 | |
| SCHEMBL8809624 | 0.80 | CTSL (0.40) | CTSKCAPN1CTSSCTSLCTSB | |
| SCHEMBL8407590 | 0.80 | EPHX1 (0.37) | CAPN1SMN1; SMN2 | |
| SCHEMBL8408073 | 0.80 | EPHX1 (0.37) | CAPN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |