Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15032331 | 0.94 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL23220996 | 0.87 | TRPV4 (0.35) | TRPV4HSD11B1 | |
| SCHEMBL15032334 | 0.82 | TRPV4 (0.38) | TRPV4HSD11B1 | |
| SCHEMBL15032332 | 0.82 | TRPV4 (0.38) | TRPV4HSD11B1 | |
| SCHEMBL16487709 | 0.81 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL15032333 | 0.81 | TRPV4 (0.37) | TRPV4 | |
| SCHEMBL21862136 | 0.79 | HSD11B1 (0.36) | TRPV4HSD11B1 | |
| SCHEMBL4458414 | 0.77 | CHRNA7 (0.38) | — | |
| SCHEMBL23663812 | 0.77 | TRPV4 (0.32) | TRPV4HSD11B1 | |
| Hydrochloric Acid SCHEMBL3041445 | 0.75 | CHRNA7 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000872-A1 | 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO(4,5)DECANE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 1997-01-09 | — | — | WO | disclosed |