Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 9/20 | 0.47 |
| ▸ | CA2 | P00918 | 9/20 | 0.47 |
| ▸ | CA9 | Q16790 | 8/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8811515 | 0.93 | ALDH1A1 (0.60) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL16013011 | 0.88 | DGKA (0.65) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL16013124 | 0.88 | DGKA (0.65) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL16023755 | 0.85 | DGKA (0.59) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL1443722 | 0.83 | TSHR (0.75) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL3092383 | 0.83 | TSHR (0.75) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL11748392 | 0.83 | TSHR (0.75) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| Methanesulfonic Acid Dodecyl Ester SCHEMBL2223590 | 0.83 | TSHR (0.75) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL140845 | 0.83 | TSHR (0.75) | LMNATSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL11225069 | 0.83 | TSHR (0.75) | LMNATSHRKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |