Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809686 | 0.92 | HTR6 (0.45) | PPARGFFAR1HTR6MAPTMGAM | |
| SCHEMBL8809627 | 0.90 | PPARG (0.41) | PPARGFFAR1HTR6MAPTCA2 | |
| SCHEMBL8808808 | 0.86 | PPARG (0.39) | PPARGFFAR1HTR6MAPTCA2 | |
| SCHEMBL8810436 | 0.86 | PPARG (0.40) | PPARGFFAR1HTR6MAPTCA2 | |
| SCHEMBL8810752 | 0.86 | PPARG (0.45) | PPARGFFAR1HTR6MAPTALDH1A1 | |
| SCHEMBL8809446 | 0.85 | PPARG (0.42) | PPARGFFAR1HTR6MAPTCA2 | |
| SCHEMBL8813817 | 0.85 | FFAR1 (0.43) | PPARGFFAR1HTR6MAPTCA2 | |
| SCHEMBL8685830 | 0.84 | PPARG (0.47) | PPARGFFAR1HTR6MAPTCA2 | |
| SCHEMBL8811079 | 0.84 | KDM1A (0.42) | PPARGFFAR1MAPT | |
| SCHEMBL8810925 | 0.84 | PPARG (0.43) | PPARGFFAR1MAPTCA2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | claimed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |