Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
| ▸ | GLRB | P48167 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8808968 | 0.89 | PPARG (0.41) | KDM1APPARGFFAR1C5AR1MAPT | |
| SCHEMBL8808926 | 0.89 | KDM1A (0.48) | KDM1APPARGFFAR1GLRA3GLRB | |
| SCHEMBL8809686 | 0.87 | HTR6 (0.45) | KDM1APPARGFFAR1MAPT | |
| SCHEMBL8813433 | 0.85 | PPARG (0.52) | PPARGFFAR1MAPT | |
| SCHEMBL8812480 | 0.84 | PPARG (0.41) | PPARGFFAR1MAPT | |
| SCHEMBL8813817 | 0.84 | FFAR1 (0.43) | PPARGFFAR1MAPT | |
| SCHEMBL8810637 | 0.84 | PPARG (0.43) | PPARGFFAR1MAPT | |
| SCHEMBL8685830 | 0.84 | PPARG (0.47) | PPARGFFAR1MAPT | |
| SCHEMBL8809588 | 0.83 | PARP1 (0.47) | PPARGFFAR1MAPT | |
| SCHEMBL8809627 | 0.83 | PPARG (0.41) | PPARGFFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | claimed |
| CN-1167111-A | Thiazolidinedione derivatives, method for preparing derivatives and pharmaceutical compositions containing same | SENGA PHARMACEUTICAL LAB INC (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |