SCHEMBL8812704

SCHEMBL8812704

NC(=O)C(CO)(CO)CO

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.33
ALDH1A1 P00352 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
OR51E2 Q9H255 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.32
FGFR4 P22455 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
USP2 O75604 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
GLA P06280 1/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16163571 0.82 CYP4F2 (0.33) LMNAALOX15BLMPMP22
SCHEMBL7511555 0.82 CYP4F2 (0.33) LMNAALOX15BLMPMP22
SCHEMBL9559979 0.78 TSHR (0.33) LMNAMEN1KMT2ATSHRALOX15
SCHEMBL16934848 0.78 CYP4F2 (0.39) TDP1
Ammonia Solution, Strong SCHEMBL28532265 0.76 LMNA (0.38) LMNAHSD17B10
SCHEMBL9358441 0.72 SOAT1 (0.39) MEN1KMT2AKDM4ETP53CYP1A2
SCHEMBL1759045 0.72 CAMK2A (0.42) LMNAALDH1A1MEN1KMT2ATSHR
SCHEMBL9362376 0.71 LMNA (0.33) LMNAALDH1A1TDP1OR51E2MEN1
SCHEMBL10923668 0.69 ALDH1A1 (0.31) ALDH1A1TP53CYP3A4
SCHEMBL175495 0.69 HTT (0.45) ALDH1A1TSHRFGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024256192-A1 PURIFICATION OF ENVELOPED OR MEMBRANOUS BIOLOGICAL PARTICLES CYTIVA BIOPROCESS R&D AB (SE) 2024-12-19 WO claimed
WO-2024256192-A1 PURIFICATION OF ENVELOPED OR MEMBRANOUS BIOLOGICAL PARTICLES CYTIVA BIOPROCESS R&D AB (SE) 2024-12-19 WO disclosed
CN-104487433-A Triazolone compounds as mpges-1 inhibitors GLENMARK PHARMACEUTICALS SA 2015-04-01 CN disclosed
CN-101248151-B Aqueous binder for inorganic fiber and thermal and/or acoustical insulation material using the same ASAHI FIBREGLASS CO 2010-11-17 CN disclosed
CN-101248151-A Aqueous binder for inorganic fiber and thermal and/or acoustical insulation material using the same ASAHI FIBREGLASS CO (JP) 2008-08-20 CN disclosed
EP-0799208-A1 PYRIDINE AND PYRAZINEDICARBOXYLIC-ACID DERIVATIVES AS CELL PROLIFERATION REGULATORS NYCOMED IMAGING AS (NO) 1997-10-08 EP disclosed
WO-1996019457-A1 PYRIDINE AND PYRAZINEDICARBOXYLIC-ACID DERIVATIVES AS CELL PROLIFERATION REGULATORS NYCOMED IMAGING AS (NO) 1996-06-27 WO disclosed