Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790892 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1TSHRHSD17B10NPC1 | |
| SCHEMBL20595118 | 0.78 | HSD17B10 (0.46) | KDM4EALDH1A1TSHRHSD17B10NPC1 | |
| SCHEMBL1135831 | 0.78 | ESR1 (0.44) | KDM4EALDH1A1TSHRMAPTC5AR1 | |
| SCHEMBL16737186 | 0.77 | KDM4E (0.39) | KDM4EALDH1A1TSHRMAPTC5AR1 | |
| SCHEMBL9543595 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1TSHRMAPTMEN1 | |
| SCHEMBL2028648 | 0.76 | KMT2A (0.36) | KDM4EALDH1A1TSHRNPC1RECQL | |
| SCHEMBL8812805 | 0.75 | HSD17B10 (0.43) | ALDH1A1TSHRHSD17B10NPC1RECQL | |
| SCHEMBL11076565 | 0.75 | KDM4E (0.45) | KDM4EALDH1A1TSHRHSD17B10NPC1 | |
| SCHEMBL29320854 | 0.74 | HSD17B10 (0.44) | ALDH1A1TSHRHSD17B10NPC1RECQL | |
| SCHEMBL8893719 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1TSHRHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663441-A | Production of mono-N-alkyl-dinitroalkylanilines and N-alkyl-dinitroaniline derivatives | SRM CHEMICAL, LTD. CO. (US) | 1997-09-02 | — | — | US | claimed |
| WO-1997001527-A1 | PRODUCTION OF MONO-N-ALKYL-DINITROALKYLANILINES AND N-ALKYL-DINITROANILINE DERIVATIVES | SYNTECH LTD. CO. (US) | 1997-01-16 | — | — | WO | claimed |
| US-5663441-A | Production of mono-N-alkyl-dinitroalkylanilines and N-alkyl-dinitroaniline derivatives | SRM CHEMICAL, LTD. CO. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1997001527-A1 | PRODUCTION OF MONO-N-ALKYL-DINITROALKYLANILINES AND N-ALKYL-DINITROANILINE DERIVATIVES | SYNTECH LTD. CO. (US) | 1997-01-16 | — | — | WO | disclosed |
| US-4395572-A | Process for preparing N-alkyl-nitroanilines | UNION CARBIDE CORPORATION (US) | 1983-07-26 | — | — | US | disclosed |
| US-4289907-A | Process for preparing N-alkyl-nitroanilines | UNION CARBIDE CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |