Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790892 | 0.80 | KDM4E (0.50) | KDM4EMAPTSNCAALDH1A1KMT2A | |
| SCHEMBL1694355 | 0.80 | ALDH1A1 (0.48) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL22804500 | 0.79 | TDP1 (0.42) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL16832016 | 0.78 | ALDH1A1 (0.46) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL16832014 | 0.78 | ALDH1A1 (0.46) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL28783807 | 0.78 | HCAR3 (0.48) | ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL8618010 | 0.78 | ALDH1A1 (0.44) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8812752 | 0.77 | KDM4E (0.44) | KDM4EMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL7162154 | 0.76 | TSHR (0.41) | KDM4EALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL11498178 | 0.75 | TRPM8 (0.53) | KDM4EALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013067-A1 | 4-SUBSTITUTED PIPERIDINECARBOXYLIC ACID ESTERS: INHIBITION OF CHOLESTEROL ABSORPTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-07-08 | — | — | WO | disclosed |