Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028644 | 0.90 | KDM4E (0.42) | KDM4EKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL4790892 | 0.75 | KDM4E (0.50) | KDM4EKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8812752 | 0.75 | KDM4E (0.44) | KDM4EKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9543595 | 0.74 | KDM4E (0.50) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9772660 | 0.72 | KDM4E (0.41) | KDM4EKMT2ARAB9AMEN1MAPT | |
| SCHEMBL9592847 | 0.70 | KDM4E (0.41) | KDM4EMAPTALDH1A1HSD17B10C5AR1 | |
| SCHEMBL11070310 | 0.70 | CYP19A1 (0.46) | KDM4EKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL29320854 | 0.69 | HSD17B10 (0.44) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL8893719 | 0.69 | KDM4E (0.44) | KDM4EKMT2ARAB9AMAPTALDH1A1 | |
| SCHEMBL8444568 | 0.68 | KDM4E (0.42) | KDM4EKMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027555-B1 | PROCESS FOR THE PREPARATION OF DIPHENYL ETHERS | CELAMERCK GmbH & Co. KG (DE) | 1984-01-04 | — | — | EP | disclosed |