Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3530485 | 0.82 | MAPT (0.62) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL7375872 | 0.80 | KMT2A (0.54) | MAPTMEN1KMT2ASMN1; SMN2HDAC2 | |
| SCHEMBL1548172 | 0.77 | MAPT (1.00) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL11591501 | 0.76 | HDAC1 (0.71) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL3102961 | 0.76 | MAPT (0.67) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL29886123 | 0.76 | MAPT (0.67) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL3529060 | 0.75 | MAPT (0.82) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL8528829 | 0.75 | MAPT (0.69) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL29088261 | 0.75 | MAPT (0.69) | MAPTCYP1A2CYP2C9CYP2C19MEN1 | |
| Hydrochloric Acid SCHEMBL3532051 | 0.75 | MAPT (0.65) | MAPTCYP1A2CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |