Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8809338 | 0.81 | ERN1 (0.39) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6222364 | 0.80 | HIF1A (0.35) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8812701 | 0.80 | GAA (0.44) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8810946 | 0.78 | TRPV4 (0.38) | ALDH1A1TP53MEN1KMT2A | |
| SCHEMBL8813338 | 0.77 | ERN1 (0.43) | TDP1ALDH1A1MAPTMEN1POLB | |
| SCHEMBL8811667 | 0.77 | TSHR (0.39) | TDP1ALDH1A1MAPTTP53MEN1 | |
| SCHEMBL6223713 | 0.76 | TSHR (0.38) | TDP1TP53MEN1KMT2A | |
| SCHEMBL8813549 | 0.75 | KMT2A (0.35) | TDP1ALDH1A1MAPTMEN1POLB | |
| SCHEMBL8812863 | 0.75 | PTGER1 (0.46) | MEN1KMT2A | |
| SCHEMBL6223474 | 0.74 | ACP3 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997000872-A1 | 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO(4,5)DECANE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 1997-01-09 | — | — | WO | disclosed |