Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292090 | 0.88 | HTT (0.39) | HTTHCRTR2ALDH1A1TSHRLMNA | |
| SCHEMBL7576144 | 0.86 | HTT (0.36) | HTTHCRTR2CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7573013 | 0.86 | KDM4E (0.36) | HTTHCRTR2CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7574484 | 0.86 | HTT (0.35) | HTTHCRTR2HSD11B1CACNA1FCACNA1D | |
| SCHEMBL8814798 | 0.85 | HTT (0.36) | HTTHCRTR2CACNA1FCACNA1DCACNA1S | |
| SCHEMBL8814793 | 0.85 | HTT (0.36) | HTTHCRTR2CACNA1FCACNA1DCACNA1S | |
| SCHEMBL8747816 | 0.85 | ELANE (0.42) | HTTHCRTR2ALDH1A1TSHRLMNA | |
| SCHEMBL6292089 | 0.83 | TSHR (0.38) | HTTHCRTR2ALDH1A1TSHRLMNA | |
| SCHEMBL9114894 | 0.82 | PPARG (0.38) | HTTALDH1A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL8492187 | 0.81 | ALDH1A1 (0.35) | HTTCACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023491-A1 | NEW HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-03 | — | — | WO | disclosed |