Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890586 | 0.90 | ALDH1A1 (0.37) | ELANETSHRHTTHCRTR2ALDH1A1 | |
| SCHEMBL6292090 | 0.89 | HTT (0.39) | ELANETSHRHTTHCRTR2ALDH1A1 | |
| SCHEMBL6292089 | 0.87 | TSHR (0.38) | ELANETSHRHTTHCRTR2ALDH1A1 | |
| SCHEMBL8493474 | 0.86 | TSHR (0.37) | ELANETSHRHTTHCRTR2ALDH1A1 | |
| SCHEMBL9116296 | 0.85 | TSHR (0.36) | ELANETSHRHTTHCRTR2ALDH1A1 | |
| SCHEMBL8816612 | 0.85 | TP53 (0.41) | ELANETSHRHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL8488004 | 0.85 | HTT (0.45) | TSHRHTTALDH1A1RAB9ANPC1 | |
| SCHEMBL8813481 | 0.85 | HTT (0.39) | TSHRHTTHCRTR2ALDH1A1RAB9A | |
| SCHEMBL9115275 | 0.84 | TSHR (0.36) | ELANETSHRHTTHCRTR2ALDH1A1 | |
| SCHEMBL8491674 | 0.84 | HTT (0.39) | TSHRHTTHCRTR2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027187-A1 | ISOXAZOLE AND 2-CYANO-1,3-DIONES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-31 | — | — | WO | disclosed |
| WO-1997023491-A1 | NEW HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-03 | — | — | WO | disclosed |
| EP-0759911-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031446-A1 | 4-BENZOYLISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-11-23 | — | — | WO | disclosed |