Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 4/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.36 |
| ▸ | STK17B | O94768 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CDK7 | P50613 | 2/20 | 0.36 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.36 |
| ▸ | CAMK4 | Q16566 | 2/20 | 0.36 |
| ▸ | MAPK15 | Q8TD08 | 2/20 | 0.36 |
| ▸ | PNPLA2 | Q96AD5 | 2/20 | 0.36 |
| ▸ | HIPK3 | Q9H422 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685246 | 0.88 | PARP1 (0.57) | PARP1MEN1KMT2APIM1PIM3 | |
| SCHEMBL8813612 | 0.88 | PARP1 (0.57) | PARP1MEN1KMT2APIM1PIM3 | |
| SCHEMBL8813512 | 0.86 | ALDH1A1 (0.53) | PARP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8809827 | 0.86 | PARP1 (0.45) | PARP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8685967 | 0.85 | PARP1 (0.50) | PARP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8811879 | 0.83 | PARP1 (0.43) | PARP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8810454 | 0.83 | PARP1 (0.43) | PARP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8810236 | 0.83 | ALDH1A1 (0.45) | PARP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8813934 | 0.79 | PARP1 (0.48) | PARP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8809411 | 0.79 | PARP1 (0.41) | PARP1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |