Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | BHMT | Q93088 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814011 | 1.00 | BLM (0.45) | BLMACE2BHMTGPR84MAPT | |
| SCHEMBL9506131 | 0.98 | BHMT (0.43) | BLMACE2BHMTGPR84MAPT | |
| SCHEMBL15514456 | 0.93 | GPR84 (0.45) | BLMACE2BHMTGPR84MAPT | |
| SCHEMBL10952672 | 0.91 | GPR84 (0.48) | BLMACE2BHMTGPR84MAPT | |
| SCHEMBL27884969 | 0.91 | GPR84 (0.48) | BLMACE2BHMTGPR84MAPT | |
| SCHEMBL13741106 | 0.89 | BHMT (0.46) | ACE2BHMTGPR84FFAR1 | |
| SCHEMBL14360558 | 0.89 | BHMT (0.48) | BLMACE2BHMTGPR84LMNA | |
| SCHEMBL15514538 | 0.87 | ACE2 (0.47) | BLMACE2BHMTGPR84MAPT | |
| SCHEMBL2353062 | 0.84 | BLM (0.63) | BLMACE2BHMTLMNA | |
| Phytanic Acid SCHEMBL7889 | 0.84 | BLM (0.63) | BLMACE2BHMTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691319-A | ANTICARCINOGENIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0536936-B1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | SANKYO CO (JP) | 1996-08-14 | — | — | EP | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |