Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397665 | 0.73 | SMN1; SMN2 (1.00) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL397664 | 0.73 | SMN1; SMN2 (1.00) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL11892099 | 0.73 | SMN1; SMN2 (1.00) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL23607616 | 0.70 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL21777545 | 0.70 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL13244119 | 0.68 | SMN1; SMN2 (0.61) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL821206 | 0.67 | ALDH1A1 (0.79) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL4861458 | 0.67 | LMNA (0.60) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL4861456 | 0.67 | LMNA (0.60) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL6858182 | 0.67 | KDR (0.57) | ALDH1A1LMNASMN1; SMN2L3MBTL1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997019090-A1 | PYRAZOLE- AND PIPERIDINE-CONTAINING COMPOUNDS AND THEIR METAL COMPLEXES AS LIGHT STABILIZERS | UV STAB LTD. (IL) | 1997-05-29 | — | — | WO | disclosed |