Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.78 |
| ▸ | MLNR | O43193 | 1/20 | 0.78 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.78 |
| ▸ | EGFR | P00533 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.78 |
| ▸ | FYN | P06241 | 1/20 | 0.78 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.78 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.78 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.78 |
| ▸ | HTR1A | P08908 | 1/20 | 0.78 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.78 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.78 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.78 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.78 |
| ▸ | DRD2 | P14416 | 1/20 | 0.78 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.78 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL10764614 | 0.96 | NPC1 (0.72) | NPC1MLNRNR1I2EGFRLMNA | |
| SCHEMBL6101514 | 0.91 | ADRA1D (0.81) | NPC1MLNRNR1I2EGFRLMNA | |
| SCHEMBL28837720 | 0.91 | ADRA1D (0.72) | NPC1MLNRNR1I2EGFRLMNA | |
| Carebastine SCHEMBL18538 | 0.90 | LMNA (0.85) | NPC1MLNRNR1I2EGFRLMNA | |
| SCHEMBL28837719 | 0.90 | ADRA1D (0.73) | NPC1MLNRNR1I2EGFRLMNA | |
| SCHEMBL28837710 | 0.89 | ADRA1D (0.78) | NPC1MLNRNR1I2EGFRLMNA | |
| SCHEMBL28837707 | 0.89 | ADRA1D (0.78) | NPC1MLNRNR1I2EGFRLMNA | |
| SCHEMBL28837716 | 0.89 | NPC1 (0.69) | NPC1MLNRNR1I2EGFRLMNA | |
| SCHEMBL28837725 | 0.88 | NPC1 (0.71) | NPC1MLNRNR1I2EGFRLMNA | |
| Ebastine SCHEMBL18467 | 0.88 | ADRA1D (1.00) | NPC1MLNRNR1I2EGFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997009983-A1 | PIPERIDINE DERIVATIVES AND PROCESSES FOR THEIR PRODUCTION | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-03-20 | — | — | WO | disclosed |
| EP-0134124-B1 | PIPERIDINE DERIVATIVES | FORDONAL, S.A. (ES) | 1987-10-28 | — | — | EP | disclosed |
| US-4550116-A | ANTIALLERGENS, CARDIOVASCULAR AND RESPIRATORY DISORDERS | FORDONAL, S.A. (ES) | 1985-10-29 | — | — | US | disclosed |
| EP-0134124-A1 | Piperidine derivatives | FORDONAL, S.A. (ES) | 1985-03-13 | — | — | EP | disclosed |