Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | PRKACG | P22612 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807829 | 0.73 | HSD17B10 (0.56) | KDM4EALDH1A1HPGDMCL1CYP3A4 | |
| SCHEMBL8164868 | 0.72 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDCYP3A4MAPT | |
| SCHEMBL31287389 | 0.70 | ALDH1A1 (0.31) | KDM4EALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL31121843 | 0.70 | ALDH1A1 (0.31) | KDM4EALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL9180513 | 0.68 | CYP2A6 (0.55) | KDM4EALDH1A1HPGDMCL1CYP3A4 | |
| SCHEMBL8816527 | 0.68 | KDM4E (0.39) | KDM4EALDH1A1HPGDMCL1MAPT | |
| Hydrochloric Acid SCHEMBL7409340 | 0.67 | CYP2A6 (0.53) | KDM4EALDH1A1HPGDMCL1CYP3A4 | |
| SCHEMBL8816911 | 0.67 | CA9 (0.50) | KDM4EALDH1A1HPGDMCL1CYP3A4 | |
| SCHEMBL5181911 | 0.66 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDCYP3A4MAPT | |
| SCHEMBL313224 | 0.66 | CYP2D6 (0.46) | ALDH1A1HPGDCYP3A4HSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696157-A | Sulfonated derivatives of 7-aminocoumarin | MOLECULAR PROBES, INC. (US) | 1997-12-09 | — | — | US | disclosed |