Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | ALPL | P05186 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816527 | 0.76 | KDM4E (0.39) | HSD17B10GAAGFERKDM4EMCL1 | |
| SCHEMBL8814191 | 0.73 | KDM4E (0.44) | HSD17B10GAAKDM4EMCL1ALDH1A1 | |
| SCHEMBL17716513 | 0.73 | HSD17B10 (0.55) | HSD17B10GAAGFERKDM4EMCL1 | |
| SCHEMBL4929255 | 0.72 | HSD17B10 (0.55) | HSD17B10GAAGFERKDM4EMCL1 | |
| SCHEMBL8724340 | 0.72 | GAA (1.00) | HSD17B10GAAGFERKDM4EMCL1 | |
| SCHEMBL28213200 | 0.71 | KMT2A (0.58) | HSD17B10GAAGFERKDM4EMCL1 | |
| SCHEMBL31331777 | 0.71 | MCL1 (0.70) | HSD17B10GAAGFERKDM4EMCL1 | |
| SCHEMBL8809669 | 0.70 | ESR2 (0.38) | GAAKDM4EMCL1ALDH1A1LMNA | |
| SCHEMBL4927312 | 0.70 | PDE4D (0.52) | HSD17B10GAAGFERKDM4EMCL1 | |
| SCHEMBL14511067 | 0.69 | KDM4E (0.53) | HSD17B10GAAKDM4EMCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696157-A | Sulfonated derivatives of 7-aminocoumarin | MOLECULAR PROBES, INC. (US) | 1997-12-09 | — | — | US | disclosed |