SCHEMBL8814647

SCHEMBL8814647

C=CC(=O)NCC(CCCCCCCCCC)S(=O)(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 2/20 0.57
ZDHHC2 Q9UIJ5 2/20 0.57
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
TP53 P04637 1/20 0.37
LCK P06239 1/20 0.37
PPARD Q03181 1/20 0.37
EPHX1 P07099 5/20 0.36
FAAH O00519 1/20 0.36
TGM2 P21980 1/20 0.35
GNAI3 P08754 1/20 0.35
GNAO1 P09471 1/20 0.35
GNAI1 P63096 1/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8812597 1.00 ZDHHC20 (0.57) ZDHHC20ZDHHC2CNR1CNR2THRA
SCHEMBL8812065 1.00 ZDHHC20 (0.57) ZDHHC20ZDHHC2CNR1CNR2THRA
SCHEMBL5057147 0.94 ZDHHC20 (0.51) ZDHHC20ZDHHC2CNR1CNR2THRA
SCHEMBL28273510 0.81 ZDHHC7 (0.42) ZDHHC20ZDHHC2TP53LCKPPARD
SCHEMBL6118081 0.81 ZDHHC20 (0.62) ZDHHC20ZDHHC2CNR1CNR2THRA
SCHEMBL28300 0.81 ZDHHC20 (0.44) ZDHHC20ZDHHC2TGM2ALDH1A1TSHR
SCHEMBL17171617 0.81 TSHR (0.48) ZDHHC20ZDHHC2TGM2ALDH1A1TSHR
SCHEMBL16581522 0.80 ZDHHC20 (0.54) ZDHHC20ZDHHC2CNR1CNR2THRA
SCHEMBL251116 0.80 ZDHHC20 (0.43) ZDHHC20ZDHHC2TGM2ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL139208 0.80 ZDHHC20 (0.43) ZDHHC20ZDHHC2TGM2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0439233-B2 Use of a plastic dispersion as coating for inorganic and organic particles DSM NV (NL) 1997-12-03 EP disclosed
US-5304395-A Mixing with dispersion of polymer based on vinyl aromatic monomer, unsaturated ester, sulfonate, unsaturated acid STAMICARBON B.V. (NL) 1994-04-19 US disclosed
EP-0439233-A1 Use of a plastic dispersion as coating for inorganic and organic particles DSM N.V. (NL) 1991-07-31 EP disclosed