Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL139208

C=CC(=O)NCC(CC)S(=O)(=O)O.N

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TGM2 P21980 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28300 0.98 ZDHHC20 (0.44) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL686653 0.97 ZDHHC20 (0.43) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Hydrochloric Acid SCHEMBL28069295 0.97 ZDHHC20 (0.43) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Acrylic Acid SCHEMBL7528349 0.93 ZDHHC20 (0.41) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Acrylamide SCHEMBL8157330 0.92 ZDHHC20 (0.40) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL5668122 0.91 ZDHHC20 (0.39) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Methacrylic Acid SCHEMBL160887 0.89 TSHR (0.39) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL17171617 0.87 TSHR (0.48) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
Crotonic Acid SCHEMBL1001175 0.87 ZDHHC20 (0.36) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1
SCHEMBL6684578 0.84 ZDHHC20 (0.35) ZDHHC20ZDHHC2TSHRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170224604-A1 CATIONIC/CATIONOGENIC COMB COPOLYMER COMPOSITIONS AND PERSONAL CARE PRODUCTS CONTAINING THE SAME EVONIK DEGUSSA GMBH (DE) 2017-08-10 US disclosed
EP-2558510-B1 CATIONIC/CATIONOGENIC COMB COPOLYMER COMPOSITIONS AND PERSONAL CARE PRODUCTS CONTAINING THE SAME AIR PROD & CHEM (US) 2015-05-20 EP disclosed
EP-2558510-A1 CATIONIC/CATIONOGENIC COMB COPOLYMER COMPOSITIONS AND PERSONAL CARE PRODUCTS CONTAINING THE SAME Air Products and Chemicals, Inc. (US) 2013-02-20 EP disclosed
US-20120058060-A1 Cationic/Cationogenic Comb Copolymer Compositions and Personal Care Products Containing the Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-03-08 US disclosed
WO-2011130030-A1 CATIONIC/CATIONOGENIC COMB COPOLYMER COMPOSITIONS AND PERSONAL CARE PRODUCTS CONTAINING THE SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-10-20 WO disclosed
EP-0169690-B1 CYCLIZATION OF ACRYLIC FIBER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-09-13 EP disclosed
EP-0172448-A2 Solid lithium and ammonium salts of poly(acrylamidomethylpropanesulfonic acid) and use thereof to thicken highly polar organic solvents HENKEL CORPORATION (a Delaware corp.) (US) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170224604-A1 CATIONIC/CATIONOGENIC COMB COPOLYMER COMPOSITIONS AND PERSONAL CARE PRODUCTS CONTAINING THE SAME C9, CUTA, ZYX ZDHHC20 698/4885ZDHHC2 1073/4885TSHR 2653/4885
US-20120058060-A1 Cationic/Cationogenic Comb Copolymer Compositions and Personal Care Products Containing the Same C9, CUTA, ZYX ZDHHC20 698/4885ZDHHC2 1073/4885TSHR 2653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.