Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIF5B | P33176 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670111 | 0.84 | POLB (0.42) | POLBNPC1CLCN2CYP1A2ALDH1A1 | |
| SCHEMBL10786785 | 0.81 | POLB (0.43) | POLBNPC1CYP1A2PEPDALDH1A1 | |
| SCHEMBL28784403 | 0.80 | CLCN2 (0.44) | POLBNPC1CLCN2CYP1A2ALDH1A1 | |
| SCHEMBL130240 | 0.78 | PDK1 (0.42) | TSHRLMNAHTT | |
| SCHEMBL5676817 | 0.77 | SMN1; SMN2 (0.58) | NPC1CYP1A2ALDH1A1RAB9AHPGD | |
| SCHEMBL8117273 | 0.76 | PDK1 (0.43) | TSHRLMNAHTT | |
| SCHEMBL14959613 | 0.75 | RET (0.40) | NPC1ALDH1A1GAAALOX15TSHR | |
| SCHEMBL8101756 | 0.73 | CA1 (0.44) | — | |
| SCHEMBL1954787 | 0.73 | POLB (0.46) | POLBNPC1CYP1A2ALDH1A1GAA | |
| SCHEMBL29581696 | 0.73 | POLB (0.46) | POLBNPC1CYP1A2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997030968-A1 | NOVEL AMINOPHENOL DERIVATIVES AND THEIR USE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-08-28 | — | — | WO | disclosed |