Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581696 | 0.84 | POLB (0.46) | POLBHSD17B10NPC1RAB9ATSHR | |
| SCHEMBL1954787 | 0.84 | POLB (0.46) | POLBHSD17B10NPC1RAB9ATSHR | |
| SCHEMBL4826054 | 0.82 | ALDH1A1 (0.52) | POLBHSD17B10NPC1RAB9ATSHR | |
| SCHEMBL8814740 | 0.81 | POLB (0.41) | POLBPEPDHSD17B10NPC1RAB9A | |
| SCHEMBL2938763 | 0.81 | POLB (0.43) | POLBPEPDHSD17B10NPC1RAB9A | |
| SCHEMBL11884965 | 0.81 | L3MBTL1 (0.40) | POLBHSD17B10TSHRTP53HTT | |
| SCHEMBL28784403 | 0.79 | CLCN2 (0.44) | POLBNPC1RAB9ALMNAGAA | |
| SCHEMBL11745220 | 0.78 | ALDH1A1 (0.50) | POLBNPC1RAB9ALMNATP53 | |
| SCHEMBL11739281 | 0.77 | ALDH1A1 (0.38) | HSD17B10TSHRLMNATP53HTT | |
| SCHEMBL7565185 | 0.77 | MAPT (0.42) | TP53HTTMAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948596-A | Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler | SOCIETE ANONYME DITE: L'OREAL (FR) | 1976-04-06 | — | — | US | claimed |
| US-4675130-A | HAIR DYES | L'OREAL (FR) | 1987-06-23 | — | — | US | disclosed |
| US-4248591-A | HAIR DYES | L'OREAL (FR) | 1981-02-03 | — | — | US | disclosed |
| US-4246181-A | HAIR DYE | L'OREAL (FR) | 1981-01-20 | — | — | US | disclosed |
| US-4221729-A | HAIR DYES | L'OREAL (FR) | 1980-09-09 | — | — | US | disclosed |
| US-4093806-A | HAIR DYES | L'OREAL (FR) | 1978-06-06 | — | — | US | disclosed |
| US-4046786-A | HAIR DYES | L'OREAL (FR) | 1977-09-06 | — | — | US | disclosed |
| US-3977825-A | Indoanilines in keratinic fiber dye cmpositions | L'OREAL (FR) | 1976-08-31 | — | — | US | disclosed |
| US-3953508-A | Diphenylamines for dyeing keratinous fibers | L'OREAL (FR) | 1976-04-27 | — | — | US | disclosed |
| US-3948596-A | Oxidation dye for keratinic fibers containing 2-halo-5-acetaminophenol as a coupler | SOCIETE ANONYME DITE: L'OREAL (FR) | 1976-04-06 | — | — | US | disclosed |
| US-3712158-A | DYEING HUMAN HAIR AND COMPOSITION FOR INCLUDING AN OXIDATION DYE AND HETEROCYCLIC COUPLER THEREOF | OREAL | 1973-01-23 | — | — | US | disclosed |