Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 15/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8818444 | 0.82 | ADORA2A (0.56) | TGFBR1MAPK14SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8815685 | 0.82 | TGFBR1 (0.51) | TGFBR1MAPK14 | |
| SCHEMBL8819090 | 0.81 | TGFBR1 (0.48) | TGFBR1MAPK14NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8817142 | 0.80 | TGFBR1 (0.47) | TGFBR1MAPK14 | |
| SCHEMBL8818447 | 0.80 | ADORA2A (0.54) | TGFBR1MAPK14MEN1KMT2A | |
| SCHEMBL8815690 | 0.80 | TGFBR1 (0.49) | TGFBR1MAPK14CLK4 | |
| SCHEMBL8818439 | 0.80 | TGFBR1 (0.49) | TGFBR1MAPK14KMT2A | |
| SCHEMBL8816938 | 0.79 | TGFBR1 (0.50) | TGFBR1MAPK14 | |
| SCHEMBL8819278 | 0.78 | TGFBR1 (0.47) | TGFBR1MAPK14 | |
| SCHEMBL8816582 | 0.78 | ADORA2A (0.58) | TGFBR1MAPK14SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |