Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772916 | 0.84 | L3MBTL1 (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8816476 | 0.77 | HPGD (0.55) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL4766743 | 0.77 | L3MBTL1 (0.46) | SMN1; SMN2HPGDNPC1RAB9ALMNA | |
| SCHEMBL4766513 | 0.76 | NPC1 (0.53) | SMN1; SMN2HPGDNPC1RAB9ALMNA | |
| SCHEMBL27058172 | 0.76 | SMN1; SMN2 (0.69) | SMN1; SMN2HPGDNPC1RAB9ALMNA | |
| SCHEMBL14758320 | 0.75 | HPGD (0.52) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL961840 | 0.75 | MAPT (0.47) | LMNAALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL14253679 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2HPGDNPC1RAB9APOLB | |
| SCHEMBL14253697 | 0.75 | ALDH1A1 (0.55) | SMN1; SMN2HPGDNPC1RAB9ALMNA | |
| SCHEMBL29300397 | 0.74 | L3MBTL1 (0.71) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997029114-A1 | BIOTIN-CONTAINING COMPOUNDS, BIOTINYLATION REAGENTS AND METHODS | BOARD OF REGENTS OF THE UNIVERSITY OF WASHINGTON (US) | 1997-08-14 | — | — | WO | disclosed |