SCHEMBL8815064

SCHEMBL8815064

CC1(C)CC(C)(c2ccc(O)cc2)c2cc(O)c(C(C)(C)c3ccc(O)cc3)cc21

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.39
ESR1 P03372 4/20 0.39
ESR2 Q92731 4/20 0.39
CYP3A4 P08684 2/20 0.39
AR P10275 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR6 P50406 1/20 0.39
ESRRG P62508 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 1/20 0.35
RXRB P28702 1/20 0.33
LMNA P02545 1/20 0.32
TYR P14679 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8767794 0.83 ESR1 (0.37) RXRAESR1ESR2CYP3A4TSHR
SCHEMBL18399471 0.82 HSP90AA1 (0.33) ESR1ESR2HSD17B10ALDH1A1LMNA
SCHEMBL7127931 0.82 ESR1 (0.37) RXRAESR1ESR2CYP3A4AR
SCHEMBL18400653 0.81 SMN1; SMN2 (0.33) ESR1ESR2
SCHEMBL3417210 0.77 ALDH1A1 (0.41) CYP3A4HPGDTSHRHSD17B10ALDH1A1
SCHEMBL7996227 0.74 ALDH1A1 (0.38) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL728580 0.74 ALDH1A1 (0.38) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL7996188 0.74 ALDH1A1 (0.38) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL29459356 0.74 ALDH1A1 (0.38) ESR1ESR2CYP3A4ALDH1A1LMNA
SCHEMBL728078 0.74 ALDH1A1 (0.38) ESR1ESR2CYP3A4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9278696-A None JP disclosed
JP-H09278696-A PHENOL DERIVATIVE AND ITS PRODUCTION MITSUI TOATSU CHEM INC 1997-10-28 JP disclosed