SCHEMBL728580

SCHEMBL728580

CC1(C)CC(C)(c2ccc(O)cc2)c2cc(O)ccc21

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
ESR1 P03372 4/20 0.37
ESR2 Q92731 4/20 0.37
OPRM1 P35372 10/20 0.35
OPRK1 P41145 5/20 0.34
OPRD1 P41143 5/20 0.34
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MRGPRX2 Q96LB1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29459356 1.00 ALDH1A1 (0.38) ALDH1A1LMNACYP3A4ESR1ESR2
SCHEMBL7996188 1.00 ALDH1A1 (0.38) ALDH1A1LMNACYP3A4ESR1ESR2
SCHEMBL7996227 1.00 ALDH1A1 (0.38) ALDH1A1LMNACYP3A4ESR1ESR2
SCHEMBL728078 0.93 ALDH1A1 (0.38) ALDH1A1LMNACYP3A4ESR1ESR2
SCHEMBL12760926 0.92 NR3C1 (0.39) ALDH1A1LMNACYP3A4ESR1ESR2
SCHEMBL13223997 0.88 PKM (0.41) ESR1ESR2MMP2MMP9
SCHEMBL27690764 0.88 RARA (0.38) ESR1ESR2
SCHEMBL3412367 0.88 ATM (0.45) ALDH1A1LMNACYP3A4ESR2
SCHEMBL7777156 0.87 MEN1 (0.36) ALDH1A1LMNACYP3A4ESR1ESR2
SCHEMBL8767794 0.86 ESR1 (0.37) ALDH1A1LMNACYP3A4ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1031 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391795-B2 Polymerizable composition, and copolycarbonate ester and method for producing same SK CHEMICALS CO., LTD. (KR) 2025-08-19 US claimed
EP-4050053-B1 ISOPROPYLIDENEDIPHENOL-BASED POLYETHERS POLYOLS, PROCESSES FOR THEIR PRODUCTION, AND FOAMS PRODUCED THEREFROM COVESTRO LLC (US) 2023-11-15 EP claimed
EP-4050052-B1 ISOPROPYLIDENEDIPHENOL-BASED POLYETHERS POLYOLS, PROCESSES FOR THEIR PRODUCTION, AND FOAMS PRODUCED THEREFROM COVESTRO LLC (US) 2023-11-15 EP claimed
EP-4050052-A1 ISOPROPYLIDENEDIPHENOL-BASED POLYETHERS POLYOLS, PROCESSES FOR THEIR PRODUCTION, AND FOAMS PRODUCED THEREFROM Covestro LLC (US) 2022-08-31 EP claimed
EP-4050053-A1 ISOPROPYLIDENEDIPHENOL-BASED POLYETHERS POLYOLS, PROCESSES FOR THEIR PRODUCTION, AND FOAMS PRODUCED THEREFROM Covestro LLC (US) 2022-08-31 EP claimed
US-20210380759-A1 POLYMERIZABLE COMPOSITION, AND COPOLYCARBONATE ESTER AND METHOD FOR PRODUCING SAME SK CHEMICALS CO., LTD. (KR) 2021-12-09 US claimed
CN-113166383-A Polymerizable composition, and copolycarbonate and method for producing same SK化学公司 2021-07-23 CN claimed
EP-1660560-B1 PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-03-23 EP claimed
EP-2649111-A1 ISOSORBIDE-CONTAINING POLYCARBONATES AND THEIR PREPARATION SABIC Innovative Plastics IP B.V. (NL) 2013-10-16 EP claimed
EP-1581594-B1 POLYCARBONATE MOLDING COMPOSITIONS AND ARTICLES WITH IMPROVED SURFACE AESTHETICS SABIC INNOVATIVE PLASTICS IP (NL) 2013-03-27 EP claimed
US-5856422-A Optically active poly(aryl)ethers containing optically pure spirobindane and indane moieties MOLECULAR OPTOELECTRONICS CORPORATION (US) 1999-01-05 US claimed
US-5830988-A Indane polyetherimides MOLECULAR OPTOELECTRONICS CORPORATION (US) 1998-11-03 US claimed
EP-0192480-B1 Bis(3-aminophenoxy) aromatics and method of preparing the same MITSUI TOATSU CHEMICALS (JP) 1994-11-23 EP claimed
EP-0471703-A1 POLYARLYLETHER KETONES CONTAINING INDANE AND USE OF AMORPHOUS POLYARLYETHER KETONES IN OPTICAL SYSTEMS HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-26 EP claimed
US-5077436-A Reacting dihydroxy derivatives with m-dinitrobenzene; reducing MITSUI TOATSU CHEMICALS, INC. (JP) 1991-12-31 US claimed
WO-1990014378-A1 POLYARLYLETHER KETONES CONTAINING INDANE AND USE OF AMORPHOUS POLYARLYETHER KETONES IN OPTICAL SYSTEMS HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-29 WO claimed
US-4948864-A Catalytic method for manufacturing aromatic polyester resin from aromatic diol, aromatic dibromide and carbon monoxide TOSOH CORPORATION (JP) 1990-08-14 US claimed
EP-0355840-A2 Method for manufacturing aromatic polyester resin Tosoh Corporation (JP) 1990-02-28 EP claimed
EP-0192480-A1 Bis(3-aminophenoxy) aromatics and method of preparing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-08-27 EP claimed
US-4334106-A CYLIZATION THE UPJOHN COMPANY (US) 1982-06-08 US claimed