Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815449 | 0.86 | TSHR (0.34) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL8817373 | 0.86 | ALDH1A1 (0.31) | ALDH1A1HTT | |
| SCHEMBL8818378 | 0.86 | PTGDR2 (0.36) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL8492575 | 0.83 | ALDH1A1 (0.39) | PKMALDH1A1SLC26A6MEN1KMT2A | |
| SCHEMBL8488359 | 0.82 | ALDH1A1 (0.37) | PKMALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL8492245 | 0.81 | PKM (0.48) | PKMALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8817069 | 0.80 | PKM (0.34) | PKMALDH1A1TSHRRAB9A | |
| SCHEMBL8815421 | 0.80 | MEN1 (0.39) | PKMALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8491581 | 0.79 | NR1H4 (0.36) | PKMALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8890952 | 0.79 | ALDH1A1 (0.33) | PKMALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027187-A1 | ISOXAZOLE AND 2-CYANO-1,3-DIONES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-31 | — | — | WO | disclosed |