Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 14/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120916 | 0.88 | TGFBR1 (0.54) | MEN1KMT2AATMTGFBR1MAPK14 | |
| SCHEMBL8818799 | 0.87 | KMT2A (0.51) | MEN1KMT2AATMTGFBR1MAPK14 | |
| SCHEMBL8814729 | 0.87 | NR1I3 (0.54) | MEN1KMT2ATGFBR1MAPK14LMNA | |
| SCHEMBL8817137 | 0.87 | TGFBR1 (0.54) | MEN1KMT2AATMTGFBR1MAPK14 | |
| SCHEMBL8816177 | 0.85 | NR1I3 (0.51) | TGFBR1MAPK14KDM4ELMNA | |
| SCHEMBL8815695 | 0.85 | ADORA2A (0.58) | MEN1KMT2AATMTGFBR1MAPK14 | |
| SCHEMBL8819255 | 0.85 | TGFBR1 (0.47) | MEN1KMT2AATMTGFBR1MAPK14 | |
| SCHEMBL8817436 | 0.85 | TGFBR1 (0.47) | MEN1KMT2AATMTGFBR1MAPK14 | |
| SCHEMBL8815687 | 0.84 | TGFBR1 (0.49) | MEN1KMT2AATMTGFBR1MAPK14 | |
| SCHEMBL8815723 | 0.84 | TGFBR1 (0.63) | MEN1KMT2AATMTGFBR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |