Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 1/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 12/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817137 | 0.92 | TGFBR1 (0.54) | NR1I3TGFBR1MAPK14MAPTABCB1 | |
| SCHEMBL6120916 | 0.90 | TGFBR1 (0.54) | TGFBR1MAPK14KMT2AMEN1 | |
| SCHEMBL8817436 | 0.87 | TGFBR1 (0.47) | NR1I3TGFBR1MAPK14ABCB1ABCG2 | |
| SCHEMBL8815752 | 0.87 | MEN1 (0.51) | TGFBR1MAPK14MAPTKMT2ALMNA | |
| SCHEMBL8816177 | 0.87 | NR1I3 (0.51) | NR1I3TGFBR1MAPK14ABCG2LMNA | |
| SCHEMBL8819255 | 0.87 | TGFBR1 (0.47) | TGFBR1MAPK14MAPTSMN1; SMN2ABCG2 | |
| SCHEMBL8815695 | 0.87 | ADORA2A (0.58) | TGFBR1MAPK14ABCG2KMT2AMEN1 | |
| SCHEMBL8815687 | 0.86 | TGFBR1 (0.49) | TGFBR1MAPK14KMT2ANPC1MEN1 | |
| SCHEMBL8816391 | 0.86 | ALDH1A1 (0.56) | TGFBR1MAPK14MAPTKMT2ANPC1 | |
| SCHEMBL8815723 | 0.86 | TGFBR1 (0.63) | NR1I3TGFBR1MAPK14ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |