2,3,7,8-Tetrachlorodibenzo-P-Dioxin

2,3,7,8-Tetrachlorodibenzo-P-Dioxin

SCHEMBL8815834

Clc1cc2c(cc1Cl)Oc1cc(Cl)c(Cl)cc1O2.[SiH4]

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AHR P35869 17/20 0.93
FLT1 P17948 1/20 0.93
ALPL P05186 1/20 0.39
GAA P10253 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29350382 0.96 AHR (1.00) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29364019 0.96 AHR (1.00) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL8939 0.96 AHR (1.00) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL2449395 0.93 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL6930992 0.93 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL7544600 0.93 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL1837452 0.93 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL2464843 0.93 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL10906041 0.90 AHR (0.87) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL9618549 0.87 AHR (0.81) AHRFLT1ALPLGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9036002-A None JP disclosed
JP-H0936002-A ELECTROLYTIC CONDENSER ELNA CO LTD 1997-02-07 JP disclosed