2,3,7,8-Tetrachlorodibenzo-P-Dioxin

2,3,7,8-Tetrachlorodibenzo-P-Dioxin

SCHEMBL8939

Clc1cc2c(cc1Cl)Oc1cc(Cl)c(Cl)cc1O2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AHR P35869 17/20 1.00
FLT1 P17948 1/20 1.00
ALPL P05186 1/20 0.40
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29350382 1.00 AHR (1.00) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29364019 1.00 AHR (1.00) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL8815834 0.96 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL2449395 0.96 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL2464843 0.96 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL7544600 0.96 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL1837452 0.96 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL6930992 0.96 AHR (0.93) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL10906041 0.93 AHR (0.87) AHRFLT1ALPLGAAMAPK1
2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL9618549 0.90 AHR (0.81) AHRFLT1ALPLGAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 86657 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-224284624-U Dioxin catalytic cracking system CHENGDU ENGINEERING CO.,LTD. OF CHINA LIGHT INDUSTRY (CN) 2026-05-26 CN claimed
CN-224285468-U Treatment system for waste incineration fly ash flue gas HUBEI LUSHENG ENVIRONMENTAL ENGINEERING Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-121607400-B Method and system for collaborative treatment of fly ash subsection desorption dioxin flue gas TONGJI UNIVERSITY (CN) 2026-05-26 CN claimed
CN-116651091-B Double-layer composite ceramic fiber filter tube with flue gas dust removal and nitrous oxide removal and dioxin removal functions and preparation method thereof NANJING TECH UNIVERSITY (CN) 2026-05-26 CN claimed
CN-122059686-A Method for preparing high-strength stone by high-temperature melting of fly ash and solid waste 上海煜工环保科技有限公司 2026-05-19 CN claimed
US-12630503-B2 Method for producing benzopyranone compound and novel intermediate used therein ILAB (KR) 2026-05-19 US claimed
CN-122060739-A Recombinant biological vector for detecting activation efficacy of arene receptor and application 南开大学 2026-05-19 CN claimed
CN-122057353-A Integrated treatment method and device for deep treatment and waste heat recovery of electric furnace flue gas pollutants 中国科学院过程工程研究所 2026-05-19 CN claimed
CN-121254713-B System and method for controlling composite atmosphere in gasification treatment of waste circuit board 江苏润联再生资源科技有限公司 2026-05-19 CN claimed
CN-122036214-A Recycling method of recycled solid waste for cement production 英德海螺水泥有限责任公司 2026-05-15 CN claimed
WO-1981003172-A1 NOVEL BENZO(1,4)DIOXINS,METHODS FOR THEIR PREPARATION AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS CERM CENT EUROP RECH MAUVERNAY (FR) 1981-11-12 WO claimed
US-4294996-A Method of reducing formation of chlorinated dioxins in manufacture of chlorinated phenols REICHHOLD CHEMICALS, INCORPORATED (US) 1981-10-13 US claimed
US-4287038-A Purification of chlorophenolic derived compounds UOP INC. (US) 1981-09-01 US claimed
US-4272635-A SALT FORMATION, QUICK-DRYING THE DOW CHEMICAL COMPANY (US) 1981-06-09 US claimed
EP-0027745-A1 A process for the electrochemical degradation of persistent organic compounds, with harmful or potentially harmful properties CRECONSULT LIMITED (GB) 1981-04-29 EP claimed
EP-0021294-A1 Chemical detoxification of toxic chlorinated aromatic compounds Vertac Chemical Corporation (US) 1981-01-07 EP claimed
US-4238472-A DOUBLE ANTIBODY QUANTITATIVE ANALYSIS; EMULSIFICATION USING AN ETHYLENE OXIDE ALKYLPHENOL ADDUCT UNITED STATES OF AMERICA (US) 1980-12-09 US claimed
US-4228309-A Cyclohexane extraction to remove chlorodibenzo-p-dioxins HATCHER DAVID B 1980-10-14 US claimed
US-4042499-A Liquid adsorption chromatographic apparatus and method THE DOW CHEMICAL COMPANY (US) 1977-08-16 US claimed
US-4013804-A BIOCIDE, WATER REPELLENT, ELECTROCONDUCTIVITY ANDERSEN CORPORATION (US) 1977-03-22 US claimed