Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 16/20 | 0.81 |
| ▸ | FLT1 | P17948 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL8939 | 0.90 | AHR (1.00) | AHRFLT1ALPLGAAMAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29350382 | 0.90 | AHR (1.00) | AHRFLT1ALPLGAAMAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL29364019 | 0.90 | AHR (1.00) | AHRFLT1ALPLGAAMAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL8815834 | 0.87 | AHR (0.93) | AHRFLT1ALPLGAAMAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL7544600 | 0.87 | AHR (0.93) | AHRFLT1ALPLGAAMAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL2449395 | 0.87 | AHR (0.93) | AHRFLT1ALPLGAAMAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL2464843 | 0.87 | AHR (0.93) | AHRFLT1ALPLGAAMAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL1837452 | 0.87 | AHR (0.93) | AHRFLT1ALPLGAAMAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL6930992 | 0.87 | AHR (0.93) | AHRFLT1ALPLGAAMAPK1 | |
| 2,3,7,8-Tetrachlorodibenzo-P-Dioxin SCHEMBL10906041 | 0.84 | AHR (0.87) | AHRFLT1ALPLGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4312475-A | — | — | None | — | — | JP | disclosed |
| JP-H04312475-A | DECOMPOSITION METHOD FOR DIOXIN IN INCINERATED ASH | MITSUBISHI HEAVY IND LTD | 1992-11-04 | — | — | JP | disclosed |