Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 13/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 13/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8817938 | 0.86 | P2RX3 (0.38) | P2RX3P2RX2F10PRSS1PRSS2 | |
| SCHEMBL8819588 | 0.84 | P2RX3 (0.41) | P2RX3P2RX2CSF1RWNT1GSK3B | |
| SCHEMBL8815946 | 0.83 | P2RX3 (0.39) | P2RX3P2RX2F10F2PRSS1 | |
| Hydrochloric Acid SCHEMBL8817549 | 0.79 | CHRM3 (0.40) | P2RX3P2RX2 | |
| Hydrochloric Acid SCHEMBL8441328 | 0.79 | KMT2A (0.46) | — | |
| Hydrochloric Acid SCHEMBL27362607 | 0.79 | HRH4 (0.38) | — | |
| Hydrochloric Acid SCHEMBL8815942 | 0.77 | CHEK1 (0.39) | — | |
| Hydrochloric Acid SCHEMBL8819669 | 0.76 | CHEK1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL8815918 | 0.75 | KDM4E (0.40) | — | |
| Hydrochloric Acid SCHEMBL8817535 | 0.74 | CHEK1 (0.36) | P2RX3P2RX2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027183-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | claimed |