Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 10/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 10/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8817942 | 0.85 | P2RX3 (0.36) | P2RX3P2RX2CHEK2 | |
| SCHEMBL8819588 | 0.84 | P2RX3 (0.41) | P2RX3P2RX2SCN1ASCN2ASCN3A | |
| SCHEMBL8815939 | 0.83 | P2RX3 (0.41) | P2RX3P2RX2CHEK2F2F10 | |
| Hydrochloric Acid SCHEMBL8441332 | 0.76 | KMT2A (0.42) | CHEK2 | |
| Hydrochloric Acid SCHEMBL8817541 | 0.73 | CHEK1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL8817987 | 0.72 | CHEK1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL8817967 | 0.71 | THRB (0.34) | CHEK2F2 | |
| SCHEMBL8817548 | 0.71 | P2RX3 (0.45) | P2RX3P2RX2CHEK2 | |
| SCHEMBL8818005 | 0.69 | ADRB2 (0.41) | OPRK1 | |
| Hydrochloric Acid SCHEMBL8817938 | 0.69 | P2RX3 (0.38) | P2RX3P2RX2CHEK2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027183-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | claimed |