Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3078569 | 0.78 | ALOX5 (0.66) | ALOX5ATMPRKDCPIK3CAPIK3CB | |
| SCHEMBL30320186 | 0.78 | ALOX5 (0.66) | ALOX5ATMPRKDCPIK3CAPIK3CB | |
| SCHEMBL8815969 | 0.75 | ALOX5 (0.50) | ALOX5ATMPRKDCPIK3CAPIK3CB | |
| SCHEMBL21694807 | 0.75 | ALOX5 (0.46) | ALOX5ATMPRKDCPIK3CAPIK3CB | |
| SCHEMBL23088939 | 0.73 | ALOX5 (0.45) | ALOX5ATMPRKDCPIK3CAPIK3CB | |
| SCHEMBL21694790 | 0.73 | ALOX5 (0.47) | ALOX5ATMPRKDCPIK3CAPIK3CB | |
| SCHEMBL3336771 | 0.72 | ALOX5 (0.44) | ALOX5ATMPRKDCPIK3CAPIK3CB | |
| SCHEMBL10985315 | 0.71 | ALOX5 (0.53) | ALOX5ATMPRKDCPIK3CAPIK3CB | |
| SCHEMBL17474342 | 0.71 | ALOX5 (0.58) | ALOX5ATMPRKDCPIK3CAPIK3CB | |
| SCHEMBL16164512 | 0.69 | ALOX5 (0.51) | ALOX5ATMPRKDCPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751944-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-01-08 | — | — | EP | disclosed |