Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779757 | 0.89 | ATM (0.47) | AHRTSHRALDH1A1KMT2AATM | |
| SCHEMBL5779754 | 0.89 | ATM (0.47) | AHRTSHRALDH1A1KMT2AATM | |
| SCHEMBL8815600 | 0.78 | PTPN7 (0.38) | PPIATTRATM | |
| SCHEMBL8816538 | 0.78 | HTT (0.43) | TSHRALDH1A1ATM | |
| SCHEMBL4298019 | 0.75 | ATM (0.56) | AHRTSHRALDH1A1KMT2AATM | |
| SCHEMBL8813829 | 0.74 | MEN1 (0.38) | AHRTSHRAKR1B1NOTUMPTGS2 | |
| SCHEMBL20480237 | 0.71 | PSMB8 (0.47) | CRHBPCRHR2NOTUMPTGS2 | |
| SCHEMBL7052203 | 0.71 | HDAC3 (0.44) | CRHBPCRHR2ALDH1A1PPIA | |
| SCHEMBL8814780 | 0.70 | GRM1 (0.43) | CRHBPCRHR2TSHRAKR1B1ALDH1A1 | |
| SCHEMBL10355854 | 0.70 | EDNRA (0.50) | TSHRALDH1A1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997006178-A1 | PYRIMIDINE NUCLEOSIDES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-02-20 | — | — | WO | disclosed |