Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816075 | 1.00 | CHEK1 (0.46) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8816528 | 0.96 | CHEK1 (0.44) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8816534 | 0.96 | CHEK1 (0.44) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8818120 | 0.90 | CHEK1 (0.45) | CHEK1PIM1IDO1LTKLIMK1 | |
| Diethylamine SCHEMBL8818126 | 0.87 | CHEK1 (0.42) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8818171 | 0.85 | IDO1 (0.59) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8818181 | 0.85 | IDO1 (0.59) | CHEK1PIM1IDO1LTKLIMK1 | |
| SCHEMBL8437411 | 0.84 | FERMT2 (0.49) | IDO1ALDH1A1NPSR1MAPTLMNA | |
| SCHEMBL8441871 | 0.80 | FERMT2 (0.49) | IDO1ALDH1A1NPSR1MAPTKDM4E | |
| SCHEMBL8818039 | 0.80 | CHEK1 (0.50) | CHEK1PIM1IDO1LTKLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997016194-A1 | NAPHTHYLAZO INHIBITION OF AMYLOIDOSIS | WARNER-LAMBERT COMPANY (US) | 1997-05-09 | — | — | WO | claimed |