Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441871 | 0.95 | FERMT2 (0.49) | FERMT2IDO1HTR1AADRA1DADRA1A | |
| SCHEMBL8816075 | 0.84 | CHEK1 (0.46) | IDO1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8816079 | 0.84 | CHEK1 (0.46) | IDO1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8441211 | 0.82 | IDO1 (0.54) | FERMT2IDO1ADRA1AMEN1KMT2A | |
| SCHEMBL8441204 | 0.82 | IDO1 (0.54) | FERMT2IDO1ADRA1AMEN1KMT2A | |
| SCHEMBL8816528 | 0.80 | CHEK1 (0.44) | IDO1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8816534 | 0.80 | CHEK1 (0.44) | IDO1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8441520 | 0.76 | IDO1 (0.42) | FERMT2IDO1MEN1KMT2ANPC1 | |
| SCHEMBL8437407 | 0.75 | MEN1 (0.39) | ADRA1AMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8818120 | 0.74 | CHEK1 (0.45) | IDO1HTR1AADRA1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955472-A | INHIBITION OF AMYLOID AGGREGATION IN ANIMALS AND PREVENTION OF ALZHEIMER'S DISEASE | WARNER-LAMBERT COMPANY (US) | 1999-09-21 | — | — | US | claimed |