Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120916 | 0.85 | TGFBR1 (0.54) | KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL8816391 | 0.83 | ALDH1A1 (0.56) | KMT2AALDH1A1MAPTMEN1HTT | |
| SCHEMBL27963586 | 0.82 | NPSR1 (0.65) | KMT2AMAPTMEN1HTTNPSR1 | |
| SCHEMBL8819242 | 0.81 | TGFBR1 (0.55) | KMT2AMEN1 | |
| SCHEMBL8816588 | 0.81 | KDM4E (0.50) | KMT2AALDH1A1MEN1POLBTDP1 | |
| SCHEMBL8818345 | 0.81 | ALDH1A1 (0.51) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL8819090 | 0.81 | TGFBR1 (0.48) | KMT2AALDH1A1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL8818254 | 0.79 | ADORA2A (0.58) | KMT2AALDH1A1MAPTMEN1HTT | |
| SCHEMBL8817636 | 0.79 | TGFBR1 (0.47) | KMT2AALDH1A1MEN1SMN1; SMN2KDM4E | |
| SCHEMBL8818160 | 0.79 | MEN1 (0.48) | KMT2AALDH1A1MEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066122-A1 | 2 - (PYRIDIN- 2 -YL) -QUINAZOLINE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-24 | — | — | WO | disclosed |