Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | AGXT | P21549 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11392894 | 0.88 | CA2 (0.39) | IDO1AGXTKMT2AMAOBMEN1 | |
| SCHEMBL11320245 | 0.81 | IDO1 (0.41) | IDO1AGXTCA2CA9NPC1 | |
| SCHEMBL11316154 | 0.81 | ESR1 (0.42) | KMT2AMAOBHSD17B10MAOACA2 | |
| SCHEMBL437438 | 0.79 | IDO1 (0.50) | IDO1KMT2AAPPMEN1CA2 | |
| SCHEMBL2096497 | 0.78 | TAAR1 (0.45) | IDO1AGXTMAOBHSD17B10MAOA | |
| SCHEMBL145399 | 0.77 | IDO1 (0.52) | IDO1AGXTMAPT | |
| SCHEMBL18544386 | 0.77 | LTA4H (0.39) | IDO1CA1CA2CA9NPC1 | |
| SCHEMBL513967 | 0.77 | CYP3A4 (0.52) | IDO1APP | |
| SCHEMBL9881633 | 0.77 | CA2 (0.32) | CA2CA9 | |
| SCHEMBL146541 | 0.77 | AGXT (0.52) | IDO1AGXTMAOBMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5578 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056767-B | Process and intermediates for the preparation of water-soluble taxane derivatives | 江苏恩华络康药物研发有限公司 | 2022-07-15 | — | — | CN | claimed |
| EP-2788353-B1 | CAGE AMINE LIGANDS FOR METALLO-RADIOPHARMACEUTICALS | Clarity Pharmaceuticals Ltd (AU) | 2022-05-18 | — | — | EP | claimed |
| EP-3053944-B1 | METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR | SHINETSU CHEMICAL CO (JP) | 2021-10-06 | — | — | EP | claimed |
| US-20210300932-A1 | CYCLIC PEPTIDES TARGETING ALPHA-4-BETA-7 INTEGRIN | ZEALAND PHARMA A/S (DK) | 2021-09-30 | — | — | US | claimed |
| US-11072616-B2 | Cyclic peptides targeting alpha-4-beta-7 integrin | UNIVERSITE DE MONTREAL (CA) | 2021-07-27 | — | — | US | claimed |
| CN-107922329-B | Process and intermediates for the preparation of water-soluble taxane derivatives | 江苏恩华络康药物研发有限公司 | 2020-11-24 | — | — | CN | claimed |
| CN-108147972-B | Preparation method of vipatavir intermediate and analogue thereof | 成都西岭源药业有限公司 | 2020-07-10 | — | — | CN | claimed |
| US-9822146-B2 | Process for the manufacture of degarelix and its intermediates | FERRING B.V. (NL) | 2017-11-21 | — | — | US | claimed |
| EP-2461805-B1 | SPECTINAMIDES AS ANTI-TUBERCULOSIS AGENTS | UNIV TENNESSEE RES FOUND (US) | 2017-11-01 | — | — | EP | claimed |
| EP-1845078-B1 | PROCESS FOR PRODUCING LARGE CYCLIC KETONE AND INTERMEDIATE THEREFOR | TAKASAGO PERFUMERY CO LTD (JP) | 2017-06-07 | — | — | EP | claimed |
| EP-0021585-B1 | TRUNCATED SOMATOSTATIN ANALOGS AND INTERMEDIATES THEREFOR, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE ANALOGS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-01-19 | — | — | EP | claimed |
| US-4281107-A | PARTICULARLY 5,6-DIDEOXYNEAMINE, USEFUL AS AN ANTIMICROBIAL AGENT | SUAMI T | 1981-07-28 | — | — | US | claimed |
| US-4278676-A | NERVOUS SYSTEM DISORDERS, CYCLIZATION, HYDROLYSIS | H. LUNDBECK & CO. A/S (DK) | 1981-07-14 | — | — | US | claimed |
| EP-0021585-A1 | Truncated somatostatin analogs and intermediates therefor, processes for their preparation, and pharmaceutical compositions containing the analogs | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-01-07 | — | — | EP | claimed |
| EP-0011283-A1 | New lactyl tetrapeptide, processes for preparation thereof and pharmaceutical compositions containing it | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-05-28 | — | — | EP | claimed |
| EP-0008196-A1 | Pentapeptides, processes for their preparation, intermediates used in such processes, use in pharmaceutical compositions and compositions containing them | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-02-20 | — | — | EP | claimed |
| US-4169939-A | PROCESSES FOR THE PRODUCTION OF 3',4'-DIDEOXYKANAMYCIN B | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1979-10-02 | — | — | US | claimed |
| US-4129719-A | ANTIBIOTICS | SUAMI T | 1978-12-12 | — | — | US | claimed |
| US-4125706-A | Novel process for the preparation of 1-N-(alpha-substituted-omega-aminoacyl)-3'-deoxyribostamycin | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1978-11-14 | — | — | US | claimed |
| US-4103082-A | ANTIMICROBIAL | SUAMI T | 1978-07-25 | — | — | US | claimed |