Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16690471 | 0.90 | MMP13 (0.55) | MMP13LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7599905 | 0.86 | MMP13 (0.52) | MMP13LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27993045 | 0.82 | MMP13 (0.49) | MMP13LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17280850 | 0.82 | MMP13 (0.49) | MMP13LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14036499 | 0.80 | MAPT (0.46) | MMP13LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6390519 | 0.80 | MMP13 (0.52) | MMP13ALDH1A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL1899005 | 0.79 | ALDH1A1 (0.48) | MMP13LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL23720089 | 0.77 | MMP13 (0.50) | MMP13ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10899009 | 0.77 | SMN1; SMN2 (0.44) | MMP13LMNASMN1; SMN2 | |
| SCHEMBL29160363 | 0.76 | ALDH1A1 (0.79) | LMNAALDH1A1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023215-A1 | 2-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE-SELECTIVE NMDA RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |