Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23105419 | 0.77 | ADORA1 (0.60) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL30741226 | 0.75 | ADORA3 (0.64) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL6757201 | 0.73 | NPC1 (0.62) | POLBMAPTNPC1RAB9A | |
| SCHEMBL724921 | 0.73 | NPC1 (0.62) | POLBMAPTNPC1RAB9A | |
| SCHEMBL1170898 | 0.73 | DHODH (0.54) | ALDH1A1PARP1CNR2CNR1NPC1 | |
| SCHEMBL3970640 | 0.73 | PARP1 (0.49) | ALDH1A1POLBMAPTHPGDTSHR | |
| SCHEMBL29412037 | 0.72 | PARP1 (0.80) | PARP1 | |
| SCHEMBL31027957 | 0.72 | DHODH (0.59) | ALDH1A1POLBPARP1CNR2NPC1 | |
| SCHEMBL6756134 | 0.72 | NPC1 (0.59) | POLBMAPTNPC1RAB9A | |
| SCHEMBL22982110 | 0.70 | PKN1 (0.51) | ADORA3ALDH1A1POLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997031635-A1 | METHODS OF TREATING OR PREVENTING SLEEP APNEA | ELI LILLY AND COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |