Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817218 | 1.00 | ADRB3 (0.60) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8757939 | 0.90 | ADRB3 (0.61) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8757924 | 0.90 | ADRB3 (0.61) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8818471 | 0.89 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8818458 | 0.89 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8819914 | 0.88 | ADRB1 (0.60) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7558376 | 0.85 | ADRB3 (0.82) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7558367 | 0.85 | ADRB3 (0.82) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7115574 | 0.83 | ADRB3 (0.78) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7686851 | 0.83 | ADRB3 (0.78) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997034905-A1 | PHOSPHORUS CONTAINING ARYLOXY AND ARYLTHIOPROPANOL AMINE DERIVATIVES USEFUL AS BETA ADRENORECEPTOR AGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-09-25 | — | — | WO | disclosed |