Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819588 | 0.86 | P2RX3 (0.41) | P2RX3P2RX2 | |
| SCHEMBL17823778 | 0.79 | P2RX3 (0.68) | P2RX3P2RX2 | |
| SCHEMBL6121545 | 0.79 | STS (0.53) | P2RX3P2RX2GPR119PDE4APDE4B | |
| SCHEMBL6122373 | 0.78 | GPR119 (0.51) | P2RX3P2RX2GPR119PDE4APDE4B | |
| SCHEMBL1107619 | 0.77 | GPR119 (0.49) | P2RX3P2RX2GPR119PDE4APDE4B | |
| SCHEMBL31078515 | 0.76 | PDE4B (0.48) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29826469 | 0.75 | MEN1 (0.55) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2807130 | 0.75 | MEN1 (0.55) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL240683 | 0.75 | GPR119 (0.61) | GPR119PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14127666 | 0.74 | GPR119 (0.51) | P2RX3P2RX2GPR119PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027183-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |